Research: 2020.0404: Boston University: PATHS-UP, NIFS, Texas A&M, NanoTech, Bio

Boston University

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==PATHS-UP - Creating a new generation of debauched doctors==

Led by Gerard Coté at Texas A&M University in partnership with the University of California at Los Angeles, Rice University, and Florida International University, PATHS-UP brings outstanding expertise to overcome four barriers endemic to POC devices, the need to: be field deployable, have high accuracy, have low complexity, and be affordable. The mission of PATHS-UP is defined by two overarching goals: (1) to engineer transformative, robust, and affordable technologies to improve healthcare access, enhance the quality of service and life, and reduce healthcare costs and (2) to recruit and educate a diverse group of scientists and engineers who will lead the future in developing enabling technologies to improve health in underserved communities.


PATHS-UP will develop two transformative engineered systems to monitor key biomarkers (biochemical, biophysical, and behavioral) of chronic disease: a Lab-in-your-Palm (LiyP) and a Lab-on-a-Wrist (LoaW). The LiyP will be enabled by novel amplification biochips based on nano-engineered single-molecule chain reactions combined with innovative handheld computational imaging and modular spectroscopic instruments. The LoaW will be enabled by unique, "bar-code like" biochemical marker implants (grain of rice in size) coupled with a novel wrist-worn spectral imager to visualize the implant through tissue and innovative sensors to monitor biophysical markers (cuffless blood pressure, heart rate).


The team has a passion to promote meaningful, lasting, engagement with K-College students, especially under-represented minorities and K-12 teachers in our partner underserved communities.